The coenzyme behind everything your cells do.
NAD+ (nicotinamide adenine dinucleotide) exists in every cell of your body, powering energy production, DNA repair, and mitochondrial function. Levels fall steadily with age — which is why restoring NAD+ has become a cornerstone of protocols targeting metabolism, mental sharpness, recovery, and healthy aging.
At a glance:
NAD+ (Nicotinamide Adenine Dinucleotide)
Essential coenzyme present in every cell, central to cellular energy metabolism, DNA repair, and sirtuin signaling. NAD+ exists in equilibrium with its reduced form (NADH) and serves as substrate for the sirtuin family of longevity regulators (SIRT1-7) and the PARP family of DNA repair enzymes. Cellular NAD+ levels decline significantly with age.
Acetate buffer
Maintains reconstituted solution at pH 5.0–5.5 — the range in which the peptide is most chemically stable. Degrades to water and acetate; renally cleared.
Mannitol
USP-grade bulking agent used during lyophilization. Produces a uniform cake, prevents peptide collapse during reconstitution, and has no pharmacologic activity at the doses used.
Cellular energy metabolism
NAD+ is the central electron carrier in cellular respiration. It accepts electrons during glycolysis, the citric acid cycle, and beta-oxidation, becoming NADH. NADH then donates these electrons to the electron transport chain, driving ATP production. Adequate NAD+ availability is rate-limiting for mitochondrial energy output.
Sirtuin activation
NAD+ is the obligatory cofactor for the sirtuin family (SIRT1-7) — protein deacetylases that regulate cellular stress response, mitochondrial biogenesis, gene expression, and DNA repair. Sirtuin activity is rate-limited by NAD+ availability; declining NAD+ with age is one of the proposed mechanisms by which sirtuin function decreases over time.
DNA repair (PARP cofactor)
Poly(ADP-ribose) polymerases (PARPs) consume NAD+ during DNA damage response. Adequate NAD+ supports the PARP-mediated repair of DNA strand breaks. Chronic high PARP activity (from accumulated DNA damage, inflammation, or oxidative stress) can deplete cellular NAD+ — creating a feedback loop where damage accumulates and repair capacity declines.
Cellular redox balance
The NAD+/NADH ratio is a central indicator of cellular redox state. Maintaining adequate NAD+ supports proper redox balance, which influences hundreds of metabolic enzymes. Chronic redox imbalance is associated with mitochondrial dysfunction, oxidative stress, and many age-related metabolic conditions.
“I've been with elite for 6 months and I still can't believe how better I feel everyday. These peptides feel like a cheat code to life.”
“Bespoke formulations takes the worry away from making sure what im getting is legit. It's genuinely a great feeling knowing that what im using will work specifically for me.”
“You know something is different when your doctor knows you by name. I've never felt so connected with my health and my caregiver before and its honestly liberating!”
“Since getting on NAD+ I've been a vocal advocate for its uses for longevity. I was a skeptic too until I discovered elite. The onboarding, the team, the way everything feels so catered to me definitely took the stress out of trying something new.”
“Joining Elite has transformed my life in just six months. These peptides have become my secret weapon for vitality and wellness!”
