Ipamorelin Peptide Therapy

Everything You Need To Know

Throughout the years when growth hormone levels are low, the preferred treatment has been to prescribe human growth hormone supplementation or hormone replacement therapy. In the past few years, science has revealed peptide therapy as another option for low hormone levels. 

Peptides help to naturally boost your hormone levels by a variety of functions. Ipamorelin is a peptide therapy that has been used for low growth hormone and can be helpful and subsiding the side effects. 

Since peptide therapy is relatively new, you may be unfamiliar with the ins and outs of this particular therapy. When taking any new medication or supplement, it is important to be well informed so you can make the best decision possible for you and your health. 

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Written by Elite HRT
on June 09, 2021

Medically reviewed by

Camille Freking, Regulatory Affairs Specialist, MEDICAL ADVISOR

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Throughout the years when growth hormone levels are low, the preferred treatment has been to prescribe human growth hormone supplementation or hormone replacement therapy. In the past few years, science has revealed peptide therapy as another option for low hormone levels.

Peptides help to naturally boost your hormone levels by a variety of functions. Ipamorelin is a peptide therapy that has been used for low growth hormone and can be helpful and subsiding the side effects.

Since peptide therapy is relatively new, you may be unfamiliar with the ins and outs of this particular therapy. When taking any new medication or supplement, it is important to be well informed so you can make the best decision possible for you and your health.

Keep reading to learn more about what ipamorelin is, how it works in the body, who should take it, when you will see effects from the treatment, the benefits, dosage, and where you can get it as well.

What is Ipamorelin?

Ipamorelin is a growth hormone-releasing peptide (GHRP). A peptide is simply a short chain of amino acids that are the building blocks of proteins. These peptides are short “instructions” that can help the cell to function better for a therapeutic purpose.

Ipamorelin is a peptide that is built up of only 5 amino acids, which is a relatively short chain. Even though it is shorter than some other peptides, it can still make a big impact as hormone therapy. It actually talks with the pituitary gland, a main gland in the brain, to stimulate increased production and secretion of growth hormone.

This is a great alternative or adjunct to growth hormone replacement and testosterone hormone replacement, especially since your body is using your own growth hormones instead of being supplemented with a synthetic growth hormone.

How Does Ipamorelin Work in the Body?

Ipamorelin helps to boost the body’s natural processes to release GH. The natural body process is that the hypothalamus, a gland in the brain, releases the growth hormone-releasing hormone (GHRH), which then goes to the pituitary gland. Once the pituitary gland gets this signal, it initiates the release of GH.

When ipamorelin is injected, it stimulates the pituitary gland to release more growth hormone, thus increasing the overall growth hormone levels. It essentially acts as the role of growth hormone-releasing hormone that is released by the hypothalamus. So instead of taking synthetic human growth hormones, you can utilize your body’s natural processes to boost the HGH levels.

Who Should Take Ipamorelin?

Those who have a low level of human growth hormone can really take advantage of ipamorelin. This can be something that can go undetected, but with hormone testing and recognizing the symptoms you can see if you might be a good candidate for ipamorelin therapy.

Some of the symptoms that may indicate you are a good candidate are if you have been feeling tired, anxious, depressed, have had a hard time concentrating or remembering things, and a decrease in libido.

Physical symptoms can also occur and you may see this as increased abdominal fat and reduced strength in the muscles.

So, if you have been experiencing these symptoms it is a great idea to bring them up to your health care provider ipamorelin could be a good fit for you and this will likely be confirmed with hormone testing to determine your growth hormone levels.

When Will You See Effects From Ipamorelin?

When starting a new medication or supplement it is natural to be excited about getting results quickly. But, good things can take time. When it comes to ipamorelin therapy some effects may be seen within the first month, but most often it takes three to six months to see the full effects of the therapy.

In the first month, the changes are usually more about your energy levels. After 1 month it is common to have more energy than before and feel like you have more stamina as well. This could be attributed to the deeper sleep that occurs in this first month as well.

After the second month, some physical features may also begin to change especially in your integumentary system, the system of hair, nails, and skin. You may notice fewer wrinkles than you had before which can give you a slightly younger appearance. Your nails also may thicken and feel stronger than before you started the treatment. Your body is also experiencing a boost in metabolism so your body processes are beginning to work faster than they did.

The third month commonly reveals an increased sex drive, which can help to improve your sex life and get back your youthful desires. You may also notice your brain feeling “sharper” with a little more mental clarity. Your joints may also improve and have overall better joint health.

The fourth month shows big changes and is when your boosted metabolism really shows its effects. If you increase metabolism you may notice some reduction in fat, especially in the midsection. This does not, however, equate to weight loss, and may actually result in weight gain due to increased muscle mass, leaving you feeling stronger in your day-to-day life.

In the fifth and sixth months, you will continue to see anti-aging related improvements in your skin, weight, and muscles. You will likely notice your nails, skin, and hair are stronger and healthier. Your skin may continue to reduce the amount or appearance of wrinkles on the surface and may even appear more even-toned. Muscles can continue to grow even by 10%. You may still notice less body fat, especially in the belly area.  By pairing ipamorelin with a healthy diet and exercise you can potentiate the effects and hopefully make a long-lasting impact on your health and wellness.

What Are the Benefits of Ipamorelin?

Ipamorelin has many benefits and they are similar to those of increasing growth hormone since the peptides are working to boost growth hormone levels. These benefits help to reduce the symptoms associated with low levels of growth hormones. This consists of mental and physical benefits.

For physical benefits, you will likely notice a decrease in body fat, smoother skin, and an increase in lean muscle mass. Ipamorelin is also working deep within your cells to create physical benefits that you might not be able to see like a boosted metabolism, increased cell health and the ability to repair itself, and more collagen production.

These physical processes can help to get mental benefits like better sleep, more energy, and a boosted mood. Overall, there are many benefits to ipamorelin and the effects you get will depend on what your symptoms are prior to the beginning of therapy.

What is the Common Dose of Ipamorelin?

Ipamorelin is usually administered through a subcutaneous injection. This means it is injected into the fatty tissue below the skin and above the muscle. The dosage of ipamorelin can change depending on the use and other factors such as symptoms and age. The dose ranges from 200 micrograms to 300 micrograms each time the drug is administered.

Usually, for those taking ipamorelin for age-related growth hormone deficiency, the dose will be 200 micrograms per day and it is usually administered once at night.  Your dose will be determined by your healthcare provider based on your health history and other information that they have gathered through your assessment.

Over time your dose may also change depending on how you are responding to treatment based on your symptoms and potential side effects.

Where Can You Get Ipamorelin?

You can get ipamorelin from your hormone replacement therapy provider. This could be your primary care provider, endocrinologist, or your hormone replacement specialist. After you are diagnosed with low levels of growth hormone any of these providers can prescribe you ipamorelin. You could be prescribed ipamorelin alone or you could be prescribed human growth hormone and/or other HGH peptides. This prescription can then be filled at a pharmacy or can be ordered and delivered to your home from your healthcare provider.

Conclusion

If you are experiencing any of these symptoms or have been diagnosed with low levels of growth hormone then ipamorelin therapy may be an option for you. Talk with your healthcare provider to assess your symptoms and hormone levels as well as weigh the pros and cons of taking peptide therapy.

Elite HRT offers you the opportunity to work with a hormone specialist 2 complete a thorough assessment and produce a comprehensive hormone treatment that is personalized just for you. Elite HRT understands that each person is unique and that hormone therapies are not one-size-fits-all. You can feel confident that you are working with a skilled team of individuals that has your best interest in mind and will work with you to help improve your quality of life.

Resources

Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males

Normal Physiology of Growth Hormone in Adults – Endotext – NCBI Bookshelf

Growth Hormone Deficiency Growth Hormone Deficiency.

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